Chapter 3: Biologically Inspired Spontaneous Assembly of Dendrimer Molecules
ثبت نشده
چکیده
Organized microstructures based on polyamidoamine dendrimers were created by using Single-Walled Carbon Nanotubes (SWNTs). Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM) showed that these patterns were characterized by straight and extended dendritic features. The formation of these shapes was attributed to a depletion mechanism induced by the SWNTs leading to the aggregation of the dendrimer molecules.
منابع مشابه
Biologically inspired molecular assembly lines
This paper proposes a biologically inspired ‘molecular assembly line’ — an externally programmable polymeric chain along which molecules are shuttled between chain sites along an arbitrary pathway. Our hope is to construct a scaffold that mimics biological enzymes known as polyketide synthases in their ability to physically hand-off molecules between assembly sites or domains, thereby making al...
متن کاملSynthesis and characterization of supramolecule self-assembly polyamidoamine (PAMAM) G1-G1 NH2, CO2H end group Megamer
Supramolecule self assembly polyamidoamine (PAMAM) dendrimer refers to the chemical systems made up of a discrete number of assembled molecular subunits or components. These strategies involve the covalent assembly of hierarchical components reactive monomers, branch cells or dendrons around atomic or molecular cores according to divergent/convergent dendritic branching principles, systematic f...
متن کاملEncapsulating fluorescein using adipic acid self-assembly on the surface of PPI-3 dendrimer.
A water-soluble self-assembly has been formed by associating adipic acid molecules onto the surface of the third generation poly(propyleneimine) dendrimer and this system has been used to encapsulate fluorescein.
متن کاملThermodynamics of Self - Assembly L
Self-assembly of molecules to form much larger colloidal or nanosized aggregates has received a great deal of attention the last decades or so and the number of technical applications and products based on the principle of self-assembly is still rapidly increasing. Moreover, fundamental processes in life sciences such as the properties and stability of lipid membranes and their interactions wit...
متن کاملComputational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex.
The cell surface interaction between bacterial lipopolysaccharide (LPS), Toll-like receptor 4 (TLR4) and MD-2 is central to bacterial sepsis syndromes and wound healing. We have shown that a generation (G) 3.5 polyamidoamine (PAMAM) dendrimer that was partially glycosylated with glucosamine inhibits TLR4-MD-2-LPS induced inflammation in a rabbit model of tissue scaring. However, it was a mixtur...
متن کامل